I am not particularly against racism. Or greed.
I am also not much exercised to fight envy. Or spite. Or rage.
I am mainly for virtue, and for the many specific virtues. And, thereby, against the many vices. But no one vice strikes me as inarguably “worst” — or one virtue as overwhelmingly “best.”
I suspect that those who fixate against one specific vice are almost certainly riddled with vice — often the very vice they most often excoriate. It is understandable. And it is a tell. But it is not a certainty, either. There are folks who target the one vice that they do not find tempting, in order to avoid the difficult task of restraining the vices that serve as their besetting sins.